目的 探讨全面护理干预对重症肺炎患者疗效及预后的影响。方法 选取我院2019年1月至2021年1月收治的72例重症肺炎（SP）患者作为研究对象，采用随机数字表法分成观察组和对照组两组，每组36例，对照组实施常规护理干预，观察组在对照组基础上实施全面护理干预，比较两组护理干预后临床有效率、急性生理与慢性健康评分及乳酸清除率、C反应蛋白及降钙素原水平。结果 对照组与观察组的临床有效率分别为58.34%和77.78%，观察组高于对照组，差异有统计学意义（P＜0.05）；两组干预前APACHEⅡ评分无太大差别，干“,”Objective To explore the effect of comprehensive nursing intervention on the curative effect and prognosis of patients with severe pneumonia.Methods A total of 72 patients with severe pneumonia (SP) admitted to our hospital from January 2019 to January 2021 were selected as the research objects， and they were divided into observation group and control group by random number table method， each with 36 cases， and the control group received routine nursing care. Intervention， the observation group implemented comprehensive nursing intervention on the basis of the control group， and compared the clinical effectiveness， acute physiology and chronic health scores， lactate clearance rate， C-reactive protein and procalcitonin levels after the nursing intervention between the two groups. Results The clinical effective rates of the control group and the observation group were 58.34% and 77.78%，respectively. The observation group was higher than the control group， and the difference was statistically significant (P＜0.05); there was no significant difference in APACHEⅡ scores between the two groups before the intervention， and the two groups after the intervention The APACHEⅡ scores have all been reduced， and the observation group is significantly better than the control group， the difference is statistically significant (P＜0.05); Compared with the pre-intervention， the lactic acid clearance rate， CRP and PCT levels of the observation group after the intervention were better than those of the control group，and the difference was statistically significant (P＜0.05). Conclusion The application of comprehensive care on the basis of routine care can effectively improve the clinical treatment efficiency of patients with severe pneumonia， and can improve the patients\' acute physiology and chronic health scores， and can significantly improve the patient\'s serum factor levels， which is worthy of clinical promotion.\"