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目的探讨脉冲振荡肺功能(IOS)测定在学龄前期儿童哮喘治疗中的应用价值。方法应用MasterScreen系列肺功能测定系统,对不能配合完成常规肺功能(PFT)测试的学龄前期不同病期哮喘病儿(发作组32例,缓解组30例)及正常对照儿童(20例)进行IOS测试。结果所有儿童全部完成测试。发作组与缓解组比较,除R20外,R5、R5-R20、X5、Fres、Zrs各指标差异皆有显著性(F=6.51~14.42,q=6.02~8.80,P<0.01)。缓解组R5-R20、Fres与对照组比较差异有显著性(q=5.98、6.04,P<0.01)。发作组除R20、R5-R20、Fres外,其余指标异常率与缓解组比较,差异均具有极显著性(2χ=14.60~28.61,P<0.01)。结论学龄前期儿童哮喘IOS测试有很好的可行性,IOS测定可作为哮喘病儿治疗评价中的很好的手段。
Objective To investigate the value of Pulsed Oscillatory Pulmonary Function (IOS) in the treatment of asthma in preschool children. Methods The MasterScreen series of pulmonary function test system was used to detect the prevalence of IOS in asthmatic children (32 in the attack group, 30 in the remission group) and 20 normal controls (children in the pre-school period) who failed to cooperate with the conventional pulmonary function test (PFT) test. Results All children completed the test. In addition to R20, there were significant differences in R5, R5-R20, X5, Fres and Zrs between the attack group and the relief group (F = 6.51-14.42, q = 6.02-8.80, P <0.01). There was significant difference between the remission group R5-R20 and Fres and the control group (q = 5.98, 6.04, P <0.01). Except for R20, R5-R20 and Fres in the seizure group, the differences between the other indexes were significant (2χ = 14.60-28.61, P <0.01). Conclusion IOS test in pre-school children with asthma has a good feasibility, IOS determination can be used as asthma children evaluation of good means.