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一家庭误将外用药醋酸铅一袋(约40g),当味精食用,当用完竟未发觉,致使一家四口在20多天内先后中毒发病。 1 临床资料 4例均有轻重不同恶心、呕吐、食欲不振、口中异味感、头昏、乏力、失眠、全身肌肉酸痛,便秘及持续性腹痛呈阵发性绞痛加剧等铅中毒表现。2例伴有小便困难。1例伴心悸。水肿。体查:铅容、无齿龈铅线。血压升高伴轻度黄疸1例。肝大1例。脐周或下腹均有不固定压痛。发病前均无铅接触及有关用药史。实验室检查:血红蛋白65~125g/L,网织红细胞5~12.5%;1例黄疸指数20u,1例肝功能轻度异常,尿检:蛋白+,白细胞3~6/Hp及溶血性改变各1例,尿铅分别为0.24、0.63.1.21.1.26μmoI/L(0.24者驱铅试验为31.40),尿粪卟啉+~++。
A family misuse of lead acetate outside a bag (about 40g), when MSG edible, when used up actually failed to find, resulting in a family of four poisoning in less than 20 days. 1 clinical data of 4 cases were different severity of nausea, vomiting, loss of appetite, mouth odor, dizziness, fatigue, insomnia, body muscle soreness, constipation and persistent abdominal pain was aggravated episodes of lead and other lead poisoning performance. 2 cases accompanied by difficulty in urinating. 1 case with heart palpitations. Edema. Physical examination: lead content, no gingival lead line. High blood pressure with mild jaundice in 1 case. 1 case of hepatomegaly. Umbilical or lower abdomen are not fixed tenderness. Before the onset of lead-free exposure and the history of medication. Laboratory tests: hemoglobin 65 ~ 125g / L, reticulocyte 5 ~ 12.5%; 1 case of jaundice index 20u, 1 case of mild liver dysfunction, urinalysis: protein +, white blood cells 3 ~ 6 / Hp and hemolytic changes of 1 Cases, urinary lead were 0.24,0.63.1.21.1.26μmoI / L (0.24 lead drive test was 31.40), urine coproporphyrin + ~ +.