论文部分内容阅读
目的分析南京市化学工业园区某职业人群糖尿病流行现状及相关危险因素,为职业人群制定糖尿病防治措施提供理论依据。方法采取整群随机抽样的方法于2014年6—8月对某企业的3个职业场所的所有职工进行问卷调查、体格检查和实验室检查。采用χ2检验和二元logistic回归模型分析糖尿病的危险因素。结果共调查1 084例,平均年龄为(39.58±9.61)岁,其中男性785例,女性299例,糖尿病患病率为4.24%。该职业人群糖尿病相关因素暴露率前3位为吸烟(42.90%)、超重/肥胖(42.16%)和向心性肥胖(33.95%)。单因素分析表明性别、年龄、体质指数(BMI)、家族史、高血压、高脂血症、吸烟、饮酒、向心性肥胖与糖尿病的发生相关(均P<0.05)。经多因素非条件逐步logistic回归分析表明,年龄(OR=3.038,95%CI:1.777~5.194)、家族史(OR=4.176,95%CI:1.880~9.276)、高血压(OR=2.038,95%CI:1.061~3.913)、高血脂症(OR=2.039,95%CI:1.054~3.943)、向心性肥胖(OR=3.309,95%CI:1.623~6.743)是糖尿病独立的危险因素。结论该职业人群糖尿病患病率低于全国平均水平,高龄、家族史、高血压、高脂血症和向心性肥胖是糖尿病发生的主要危险因素,应针对糖尿病危险因素采取综合防治措施。
Objective To analyze the prevalence of diabetes mellitus and related risk factors in a professional population in Nanjing Chemical Industry Park and provide theoretical basis for the prevention and treatment of diabetes in professional population. Methods A cluster random sampling method was used to conduct questionnaires, physical examinations and laboratory tests on all employees in 3 occupations of an enterprise in June-August 2014. The χ2 test and binary logistic regression model were used to analyze the risk factors of diabetes. Results A total of 1 084 cases were investigated, the average age was (39.58 ± 9.61) years, of which 785 were male and 299 were female, with a prevalence of 4.24%. The occupational population of the top three exposure-related factors of diabetes were smoking (42.90%), overweight / obesity (42.16%) and central obesity (33.95%). Univariate analysis showed that gender, age, body mass index (BMI), family history, hypertension, hyperlipidemia, smoking, alcohol consumption, central obesity were associated with the occurrence of diabetes (all P <0.05). Multivariate stepwise logistic regression analysis showed that there were significant differences in age (OR = 3.038,95% CI: 1.777-5.194), family history (OR = 4.176,95% CI 1.880-9.276) % CI: 1.061 ~ 3.913), hyperlipidemia (OR = 2.039, 95% CI: 1.054 ~ 3.943) and central obesity (OR = 3.309, 95% CI: 1.623 ~ 6.743) were independent risk factors for diabetes. Conclusion The prevalence of diabetes in the occupational population is lower than the national average. Older age, family history, hypertension, hyperlipidemia and central obesity are the major risk factors of diabetes. Comprehensive prevention and control measures should be taken according to the risk factors of diabetes.