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利多卡因由于副作用少且为时短暂,为治疗急性室性心律失常的首选药物。近来有报告小剂量利多卡因引起严重窦性心动过缓或窦性停搏。本文报告一例62岁糖尿病合并陈旧性下壁心肌梗死患者出现双向性室性心动过速,静注利多卡因50毫克,迅即恢复窦性节律(75次/分),但病人于注射后3～4分钟内,出现短暂性全身抽搐,静注安定2毫克数秒钟后转为慢性的房室连接处节律(43次/分)。进而又变为更慢而不稳
Lidocaine is the drug of choice for the treatment of acute ventricular arrhythmias due to its short and transient side effects. Recently there have been reports of low doses of lidocaine caused by severe sinus bradycardia or sinus arrest. This article reports a 62-year-old diabetic patients with old inferior myocardial infarction occurred bidirectional ventricular tachycardia, intravenous lidocaine 50 mg, and soon to restore sinus rhythm (75 beats / min), but the patients after injection of 3 ~ Within 4 minutes, transient generalized convulsions occurred. After intravenous infusion of 2 mg for several seconds, they switched to a chronic rhythmic atrioventricular junction (43 beats / min). Which in turn becomes slower and less stable