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为确定色甘酸二钠对食物变态反应的疗效,作者选择5例对摄食黄豆粉发生变态反应,但未使用激素的患者。4例引起支气管哮喘,1例引起血管神经性水肿。全部患者均在预备性的激发试验中证实。每例患者在试验前1日,停用其它药物,口服色甘酸二钠200mg。次日,在使用抗原前2小时15分钟再服1次。然后使用在预备试验中测出的引起反应的最小抗原量作激发试验。如果不能阻止变态反应症状出现,色甘酸二钠剂量应逐次递增为200、400、600mg。
To determine the efficacy of cromolyn disoproxil on food allergy, the authors selected 5 patients who had an allergic response to ingested soybean meal but did not use the hormone. 4 cases caused bronchial asthma, 1 case caused angioedema. All patients were confirmed in a preparatory challenge test. Each patient on the 1st day before the trial, disable the other drugs, oral cromolyn 200mg. The next day, use antigens 2 hours and 15 minutes before serving a second. The minimum amount of antigen that elicited the response as measured in the preliminary test was then used as the challenge test. If you can not stop the symptoms of allergy, cromolyn disodium dose should be increased sequentially 200,400,600 mg.