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目的探讨新生儿肺出血的临床特点。方法回顾性分析本院新生儿科2007年1月至2010年10月新生儿肺出血患儿的临床特点,总结新生儿肺出血患儿的胎龄、体重、原发病、血浆和呼吸机使用情况以及治疗和转归。结果共49例新生儿肺出血患儿,胎龄<30周19例(39%),30~36周17例(35%);体重<1000 g 12例(25%),1000~1499 g 22例(45%)。肺出血发生率较高的原发因素主要有新生儿肺透明膜病、窒息、肺部感染。共死亡11例,输血浆患儿31例,死亡5例;未输血浆患儿18例,死亡6例,差异有统计学意义(P<0.05)。常频机械通气35例,死亡7例;高频振荡通气14例,死亡4例,差异无统计学意义(P>0.05)。结论肺出血的发生与早产、低出生体重、肺透明膜病等缺氧性疾病及肺部感染性疾病有关,发生肺出血后应予综合治疗。
Objective To investigate the clinical features of neonatal pulmonary hemorrhage. Methods The clinical features of neonates with pulmonary hemorrhage from January 2007 to October 2010 in our hospital were analyzed retrospectively. The gestational age, weight, primary disease, plasma and ventilator usage of neonates with pulmonary hemorrhage were summarized. As well as treatment and prognosis. RESULTS: A total of 49 neonates with pulmonary hemorrhage were born in 19 patients (39%) at gestational age <30 weeks, 17 patients (35%) at 30-36 weeks, 12 patients (25%) weighing <1000 g and 1000-1499 g Example (45%). The primary causes of higher incidence of pulmonary hemorrhage are neonatal hyaline membrane disease, asphyxia, lung infection. There were 11 deaths, 31 deaths and 5 deaths. There were 18 deaths and 6 deaths in the untreated plasma. The difference was statistically significant (P <0.05). Frequent mechanical ventilation in 35 cases, 7 patients died; high-frequency oscillatory ventilation in 14 cases, 4 patients died, the difference was not statistically significant (P> 0.05). Conclusions The occurrence of pulmonary hemorrhage is related to hypoxemia such as premature delivery, low birth weight, hyaline membrane disease and pulmonary infectious diseases, and should be treated comprehensively after pulmonary hemorrhage.