据报道在白喉和破伤风类毒素的制备过程中,甲醛脱毒处理会导致蛋白结合物的产生。为此,作者将白喉和破伤风毒素混合后脱毒产物同分别脱毒后的两者混合物进行比较,在体外用十二烷基硫酸钠-聚丙烯酸胺凝胶电泳(SDS-PAGE),高压液相色谱(HPLC), It has been reported that detoxification of formaldehyde causes the production of protein conjugates during the preparation of diphtheria and tetanus toxoid. To this end, the authors diphtheria and tetanus toxin detoxification products were mixed detoxified with the mixture of the two were compared in vitro with sodium dodecyl sulfate - polyacrylamide gel electrophoresis (SDS-PAGE), high pressure Liquid chromatography (HPLC),