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目的了解人类嗜T淋巴细胞白血病病毒(human T cell leukemia virus,HTLV)在温州地区无偿献血人群中的感染情况。方法采用酶联免疫吸附实验(enzyme linked immunosorbent assay,ELISA),对2016年3-11月温州地区无偿献血者72 417人的HTLV-Ⅰ/Ⅱ抗体进行筛查,有反应性的标本进行双孔复检,复检仍有反应性的标本采用蛋白质免疫印迹实验(Western Blotting,WB)确认。结果 ELISA方法筛查抗-HTLV反应性23例,经WB实验确证9例,本地区无偿献血人群中HTLV感染率为0.01%(9/72 417)。结论温州地区无偿献血人群中存在HTLV感染,但现阶段HTLV感染率处于较低水平。
Objective To understand the infection of human T cell leukemia virus (HTLV) in the blood donors in Wenzhou area. Methods ELISA was used to screen 72 417 HTLV-Ⅰ / Ⅱ antibodies in blood donors in Wenzhou from March to November in 2016. Reactive samples were double-stained Retest, retest still reactive specimens using Western blotting (Western Blotting, WB) to confirm. Results 23 cases of anti-HTLV reactivity were screened by ELISA. Nine cases were confirmed by WB. The HTLV infection rate was 0.01% (9/72 417) in the blood donors in this area. Conclusion HTLV infection exists in the blood donors in Wenzhou area, but the infection rate of HTLV is low at this stage.