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目的探讨阴道镜联合LEEP刀诊治宫颈上皮内瘤变(CIN)的临床疗效。方法阴道镜下活检病理诊断为CIN的50例患者,具有LEEP手术指征,在阴道镜指引下行LEEP术,平均年龄38岁。术后3个月及半年复查并行宫颈液基细胞薄层制片(TCT),以后每6个月复查随访。结果手术平均时间(8±2)min;术中出血量平均(10±3.0)ml;阴道镜下活检病理诊断与LEEP术后诊断的符合率为76%(38/50),升级率为4%(2/50),降级率20%(10/50);术后3个月细胞学复查转阴率为94%,6个月复查转阴率为100%。LEEP术后无严重并发症,未出现复发。结论阴道镜联合LEEP刀在CIN的诊治疗中具有重要的价值,其操作简便、手术时间短,创伤小、疗效确切,可作为安全有效的治疗方法推广应用。
Objective To investigate the clinical efficacy of colposcopy combined with LEEP in diagnosis and treatment of cervical intraepithelial neoplasia (CIN). Methods Colposcopic biopsy diagnosis of CIN in 50 patients with LEEP surgical indications, LEEP under the guidance of colposcopy, with an average age of 38 years. Three months and six months after the operation, cervical liquid-based thin-slicing (TCT) was performed and followed up every 6 months. Results The average operation time was (8 ± 2) min. The mean intraoperative blood loss was (10 ± 3.0) ml. The coincidence rate of colposcopy biopsy and LEEP was 76% (38/50), and the upgrade rate was 4 % (2/50), and the relegation rate was 20% (10/50). The cytological examination negative conversion rate was 94% at 3 months and 100% after 6 months. LEEP no serious complications, no recurrence. Conclusions Colposcope combined with LEEP knife has important value in the diagnosis and treatment of CIN. The operation is simple, the operation time is short, the trauma is small and the curative effect is exact. It can be used as a safe and effective treatment method.