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目的探讨肝毒性中药及其药性的关系。方法查阅《中华本草》《中华药海》《中华人民共和国药典》《医药期刊全数据库》《中文科技期刊数据库》等选择其中144味中药肝毒性报告较为完整的药物,对其进行统计分析。结果《药典》中药和肝毒性中药的四气归属顺序相同,分布趋势大致相同。《药典》中523味中药归经顺序基本类似,其最大差异在于大肠经的排序顺序不对,但总体分布趋势大致相同。结论在四气五味归经方面,一般中药与肝毒性中药无明显的区别分布,说明中药药性与中药肝毒性不存在相关性。
Objective To investigate the relationship between hepatotoxicity and its drug resistance. Methods To select 144 Chinese herbal medicines with relatively complete reports of hepatotoxicity, such as “Chinese Materia Medica”, “Chinese Medicine Sea”, “Chinese Pharmacopoeia”, “Chinese Medicine Periodical Database” and “Chinese Scientific and Technical Periodical Database”, etc., were statistically analyzed. Results “Pharmacopoeia” Chinese medicine and liver toxicity of the four gas attribution in the same order, the distribution of roughly the same trend. “Pharmacopoeia” 523 flavor of traditional Chinese medicine returned to the basic similar sequence, the biggest difference is that the ordering of the large intestine by the wrong order, but the overall distribution of roughly the same trend. Conclusion In terms of four gas and five flavors, there is no obvious difference between traditional Chinese medicine and hepatotoxicity traditional Chinese medicine, indicating that there is no correlation between traditional Chinese medicine and traditional Chinese medicine hepatotoxicity.