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目的比较腹腔热灌注化学疗法(化疗)(CHPPC)和静脉化疗在晚期胃癌患者中的应用效果,以寻求最适宜的护理方案。方法选取2013年6月-2014年6月住院治疗并需要进行化疗的晚期胃癌患者60例,按照化疗方式将其分为CHPPC组和静脉化疗组,每组各30例。记录两组患者的护理方法,出院前1d记录患者对护理和治疗的满意度,评价患者化疗期间生活质量,复查并随访患者治疗1年后的腹腔转移率和生存率。结果静脉化疗组患者的生活质量低于CHPPC组(P<0.05),两组患者的满意度、腹腔转移率和1年生存率比较差异无统计学意义(P>0.05)。结论对于需要行化疗的晚期胃癌患者,虽然CHPPC操作较为复杂,价格较高,但可在不降低患者满意度的同时提高患者的生活质量。
Objective To compare the effects of intraperitoneal hyperthermic perfusion chemotherapy (CHPPC) and intravenous chemotherapy in patients with advanced gastric cancer and seek the most suitable nursing plan. Methods Sixty patients with advanced gastric cancer admitted to our hospital from June 2013 to June 2014 were enrolled in this study. Patients were divided into CHPPC group and intravenous chemotherapy group according to the chemotherapy regimen, 30 cases in each group. The nursing methods of two groups of patients were recorded. The patient’s satisfaction with nursing and treatment was recorded 1d before discharge, and the quality of life of patients during chemotherapy was evaluated. The celiac metastasis rate and survival rate after 1-year follow-up and follow-up were observed. Results The quality of life of the patients in the intravenous chemotherapy group was lower than that in the CHPPC group (P <0.05). There was no significant difference in satisfaction, peritoneal metastasis and 1-year survival between the two groups (P> 0.05). Conclusions Although CHPPC is more complicated and expensive for patients with advanced gastric cancer who need chemotherapy, it can improve the quality of life of patients without reducing patient satisfaction.