论文部分内容阅读
应用免疫组化方法观察中药消痞灵冲剂对胃癌前期病变大鼠胃粘膜癌胚抗原（ＣＥＡ）、胃粘膜及脾Ｓ－１００阳性细胞变化的影响。结果显示：与对照组相比，病变组大鼠胃粘膜ＣＥＡ阳性表达增多、增强，胃粘膜和脾之Ｓ－１００阳性细胞数明显增多，应用消痞又冲剂预防和治疗后，上述检测指标均明显降低。证实，消痞灵冲剂可抑制胃癌前期病变细胞肿瘤相关抗原的表达和影响机体的免疫功能，这可能是消痞灵冲剂对胃癌前期病变发挥防治作用的方式之一。
Immunohistochemical method was used to observe the effect of Xiaozhiling granules on changes of gastric carcinoembryonic antigen (CEA), gastric mucosa and spleen S-100 positive cells in gastric precancerous rats. The results showed that compared with the control group, the positive expression of CEA in the gastric mucosa of the lesion group was increased and enhanced, and the number of S-100 positive cells in the gastric mucosa and spleen was significantly increased. After the prevention and treatment with Xiao Yu You Granule, the above detection indicators were Obvious reduction. It was confirmed that Xiaozhiling granules can inhibit the expression of tumor-associated antigens in gastric precancerous lesions and affect the body’s immune function, which may be one of the ways that Xiaozhiling granules play a preventive and therapeutic effect on precancerous lesions of gastric cancer.