目的　研究低浓度二硫化碳 (CS2 )对接触工人生殖健康的影响 ,进一步探讨CS2 毒性作用机制。方法　对 5 0名接触CS2 浓度平均为 14 .4 6mg/m3 ,接触工龄为 8～ 13年的男工 (接触组 )和 5 0名非接触男工 (对照组 )应用放射免疫法测定其性激素水平。结果　接触组血清卵泡刺激素 (10 .94± 7.35 )IU/L明显高于对照组 (7.5 0± 5 .0 7)IU/L ,垂体催乳素(5 .72± 4 .18)ng/L极显著低于对照组 (6 .89± 4 .6 2 )ng/L ;间质细胞刺激素和睾酮两组间均无显著性差异。班的轮换不影响性激素水平。结论　CS2 对接触男工性激素分泌功能已造成一定的损伤 ,使潜在的原发性生殖机能不全的危险性增高 Objective To study the effect of low concentration carbon disulfide (CS2) on reproductive health of exposed workers and to further explore the mechanism of CS2 toxicity. Methods Fifty male workers (contact group) and 50 non-contact male workers (control group) who were exposed to CS2 for an average of 14.46 mg / m3 for a length of 8 to 13 years were tested for their sex hormones by radioimmunoassay Level. Results The IU / L of serum FSH (10.94 ± 7.35) in contact group was significantly higher than that in control group (7.5 0 ± 5.07 IU / L) and pituitary prolactin (5.72 ± 4.18) ng / L Extremely significantly lower than the control group (6.99 ± 4.62 ng / L); there was no significant difference between the two groups of interstitial cell stimulating hormone and testosterone. Class shifts do not affect sex hormone levels. Conclusions CS2 has caused certain damage to the secretion of sex hormones in contact with male workers, increasing the risk of underlying primary reproductive failure