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目前,国内外多数学者主张,对高热(特别是过高热)病人应在病因治疗的同时酌情应用激素,以迅速降温退热,改善病情,降低病死率。一、激素降温的作用机制:发热多由于各种外源性致热原(细菌及其产物、内毒素、病毒、真菌、抗原、抗原—抗体复合物、原胆烷醇酮、多核苷酸等),刺激白细胞(特别是大单核)和组织吞噬细胞释放内源性致热原进入血循环,直接作用于体温调节中枢所引起。据新近报道,激素具有:①非特
At present, most scholars at home and abroad advocate that high fever (especially overheated) patients should be treated with the hormone at the same time as the cause of treatment, in order to rapidly reduce fever, improve the condition and reduce the case fatality rate. First, the mechanism of the role of hormone cooling: fever and more due to a variety of exogenous pyrogen (bacteria and their products, endotoxins, viruses, fungi, antigens, antigen - antibody complex, the original cholanone, polynucleotides, etc. ), Stimulate white blood cells (especially large mononuclear) and tissue phagocytes release endogenous pyrogen into the blood circulation, a direct role in the regulation of the body temperature caused by the center. According to a recent report, hormones have: ① non-special