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甲状旁腺激素(PTH)通常被认为是刺激破骨细胞骨吸收从而引起骨分解代谢增强的激素,但早在30年代Selye等就报告PTH也有增加骨形成的作用。特别是最近10多年来,随着对骨质疏松症危害性认识的提高,人们在寻找有效治疗骨质疏松症药物时,对于PTH的成骨作用愈加重视。研究发现
Parathyroid hormone (PTH) is generally considered to be stimulating osteoclast bone resorption, resulting in increased catabolism of hormones, but Selye, etc. as early as the 30s reported that PTH also increased bone formation. Especially in the recent 10 years, with the increasing awareness of the dangers of osteoporosis, people are paying more attention to the osteogenesis of PTH when looking for effective treatment of osteoporosis drugs. The study found