论文部分内容阅读
目的探讨无精子症患者的血清生殖激素和染色体核型的临床诊断意义。方法检测并分析无精子症患者的染色体核型以及血清生殖激素水平。结果染色体异常总数64例,异常发生率达57.14%。性染色体异常56例,占异常总数的87.50%,常染色体异常8例,占异常总数12.50%。无精子症组卵泡刺激素(FSH)、黄体生成素(LH)、垂体催乳素(PRL)均显著高于正常精液组(P<0.01),睾酮(T)呈显著性降低(P<0.01),雌二醇(E2)无显著性变化(P>0.05)。结论对无精子症患者进行染色体核型和血清生殖激素测定对其病因分析、诊断及治疗具有重要的临床意义。
Objective To investigate the clinical significance of serum reproductive hormones and karyotypes in patients with azoospermia. Methods Detection and analysis of azoospermia in patients with chromosomal karyotype and serum reproductive hormone levels. Results The total number of chromosomal abnormalities in 64 cases, anomalous incidence of 57.14%. 56 cases of sex chromosome abnormalities, accounting for 87.50% of the total number of anomalies, autosomal abnormalities in 8 cases, accounting for 12.50% of the total number of anomalies. FSH, LH and PRL in azoospermia group were significantly higher than those in normal semen group and testosterone group (P <0.01) , Estradiol (E2) showed no significant change (P> 0.05). Conclusions It is of great clinical significance to analyze the karyotype and serum reproductive hormone in azoospermia patients for their etiological analysis, diagnosis and treatment.