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本文用放免法测定44例窒息新生儿血浆β－内啡肽（β－EP）的变化，同时测定31例正常新生儿为对照组。结果表明，窒息新生儿组血浆β－EP明显高于对照组，并发现血浆β－EP水平与Apgar评分密切相关，严重窒息组比中度窒息组血浆β－EP明显增高。在窒息组中有宫内窘迫者血浆β－EP水平高于无窘迫者，提示β－EP在围产期窒息的发病机制中起一定作用，对其治疗推荐用纳洛酮。
In this paper, 44 cases of asphyxia newborns plasma β-endorphin (β-EP) changes measured by radioimmunoassay, and 31 cases of normal newborns as control group. The results showed that plasma β-EP in neonatal asphyxia group was significantly higher than that in control group, and the plasma β-EP level was closely related to Apgar score. Serum β-EP in severe asphyxia group was significantly higher than that in moderate asphyxia group. In the asphyxia group, the level of plasma β-EP in patients with intrauterine distress was higher than those without embolism, suggesting that β-EP may play a role in the pathogenesis of perinatal asphyxia and naloxone is recommended for its treatment.