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目的:观察卡托普利治疗肺心病心力衰竭的疗效。方法:肺心病心力衰竭60例(男性42例、女性18例;年龄71±s4a).采用卡托普利6.25-25mg,po,tid。待心力衰竭控制后,减量至有效维持量,1-2wk为一个疗程,其中16例加用地高辛0.125mg,qd。另设对照组(单用地高辛0.125mg,po,qd或硝苯地平10mg,po,tid)60例作对比。结果:总有效率分别为90%和80%,经Ridit分析,2组疗效无明显差异(P>0.050).结论:使用卡托普利是一种治疗肺心病心力衰竭的有效药物。
Objective: To observe the curative effect of captopril on heart failure of pulmonary heart disease. Methods: Sixty patients with cor pulmonale heart failure (42 males and 18 females; age 71 ± s4a). Captopril 6.25-25mg, po, tid. Heart failure to be controlled, reduced to the effective maintenance dose, 1-2wk for a course of treatment, of which 16 cases plus digoxin 0.125mg, qd. Another control group (single digoxin 0.125mg, po, qd or nifedipine 10mg, po, tid) for 60 cases for comparison. Results: The total effective rates were 90% and 80% respectively. There was no significant difference between the two groups (P> 0.050) by Ridit analysis. Conclusions: Captopril is an effective drug for the treatment of heart failure due to cor pulmonale.