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组胺是肥大细胞和嗜碱性粒细胞内组氨酸脱羧基后产生的一种胺类物质 ,是肥大细胞和嗜碱性粒细胞脱颗粒的标志物 ,本研究通过组胺对人大肠肥大细胞进行体外干预 ,探讨组胺对人肥大细胞类胰蛋白酶释放的调节和可能的机制。结果发现 :1.组胺可诱导人大肠肥大细胞以非剂量依赖性的
Histamine is an amine substance produced after decarboxylation of histidine in mast cells and basophils and is a marker of degranulation of mast cells and basophils. In this study, histamine on human large intestine hypertrophy Cells in vitro intervention to explore histamine on human mast cell tryptase release regulation and possible mechanisms. The results showed that: 1. Histamine induced human colorectal mast cells in a dose-independent manner