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目的:研究临床肺部感染评分在评估无创通气治疗慢性阻塞性肺疾病急性加重期患者呼吸的衰竭疗效。方法:抽取龙川县中医院2013年6月至2015年6月收治的慢性阻塞性肺疾病急性加重期呼吸衰竭患者16例,调取患者完整临床资料,比较无创通气上机前后患者临床肺部感染评分等。结果:无创通气有效时临床肺部感染评分显著低于无创通气无效时临床肺部感染评分(P<0.05)。其中,9例患者临床肺部感染评分大于7,无创通气治疗均无效,1例患者临床肺部感染评分小于7,无创通气治疗均有效、6例患者临床肺部感染评分等于7,其中4例有效、2例无效。治疗无效患者通气治疗中断次数(1.6±0.2)次显著多于治疗有效(0.4±0.2)次(P<0.05)。治疗无效时并发症发生率25.00%高于治疗有效的12.50%(P<0.05)。结论:临床肺部感染评分可以提示无创通气治疗慢性阻塞性肺疾病急性加重期患者呼吸衰竭的治疗效果,临床肺部感染评分7可以作为判断无创通气治疗效果的参照指标。
OBJECTIVE: To study the efficacy of clinical lung infection score in evaluating respiratory failure in patients with acute exacerbation of chronic obstructive pulmonary disease by non-invasive ventilation. Methods: Totally 16 patients with acute respiratory failure and chronic obstructive pulmonary disease who were admitted to Longchuan Hospital of Traditional Chinese Medicine from June 2013 to June 2015 were recruited. The complete clinical data were collected and compared between before and after non-invasive ventilation Infection score and so on. Results: The score of clinical pulmonary infection was significantly lower in non-invasive ventilation when compared with non-invasive ventilation (P <0.05). Among them, nine patients had clinical pulmonary infection score greater than 7, non-invasive ventilation was ineffective, clinical lung infection score was less than 7 in one patient, non-invasive ventilation were effective, and 6 patients had clinical pulmonary infection score equal to 7, of which 4 Effective, 2 invalid. The number of ventilatory interruptions in patients with ineffective treatment was significantly (1.6 ± 0.2) times more effective than (0.4 ± 0.2) times (P <0.05). The incidence of complications when treatment was ineffective was 25.00% higher than that of treatment-effective 12.50% (P <0.05). Conclusion: The score of clinical pulmonary infection can indicate the therapeutic effect of noninvasive ventilation on respiratory failure in patients with acute exacerbation of chronic obstructive pulmonary disease, and the score of clinical pulmonary infection can be used as a reference index to judge the effect of noninvasive ventilation.