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目的探讨尼莫地平联合认知功能训练对急性脑脑梗死认知功能障碍患者的影响。方法选择我院2007-11～2009-11急性脑梗死认知功能障碍患者81例,将以上患者随机分为2组,观察组和对照组。对照组患者给予常规神经内科治疗,同时给予物理治疗、作业治疗等。在对照组治疗基础上,观察组给予认知功能训练和尼莫地平治疗。2组患者均治疗3个月。患者治疗前和治疗3个月后,采用神经行为认知状态测试(NCSE)量表、画钟试验(CDT)、欧洲神经功能缺损评分(ESS)、Fugl-Meyer(FMA)量表、Barthel Index对患者进行评分。结果观察组治疗3个月后NCSE总评分和画钟试验(CDT)评分分别与对照组治疗3个月后比较,差异有统计学意义(P<0.05);观察组治疗3个月后ESS评分、FAM评分和日常生活活动能力评分分别与对照组治疗3个月后比较,差异有统计学意义(P<0.05)。结论尼莫地平联合认知功能训练有助于改善急性脑脑梗死后认知功能障碍,有利于提高患者的肢体运动功能和日常生活活动能力,临床效果显著,值得借鉴。
Objective To investigate the effect of nimodipine combined with cognitive function training on cognitive dysfunction in patients with acute cerebral infarction. Methods Eighty-one patients with cognitive impairment in acute cerebral infarction from 2007-11 to 2009-11 were randomly divided into two groups: observation group and control group. Patients in the control group were given conventional neurological treatment, physical therapy and homework were given at the same time. On the basis of the control group, the observation group was given cognitive training and nimodipine treatment. Two groups of patients were treated for 3 months. Patients were treated with NCSE, CDT, ESS, FMA and Barthel Index before treatment and 3 months after treatment. Score the patient. Results After 3 months of treatment, NCSE total score and drawing bell test (CDT) score in the observation group were respectively compared with those in the control group after 3 months of treatment (P <0.05). After 3 months of treatment, the ESS score , FAM score and activities of daily living scores were compared with the control group after 3 months of treatment, the difference was statistically significant (P <0.05). Conclusion Nimodipine combined with cognitive function training can help to improve the cognitive dysfunction after acute cerebral infarction, which is beneficial to improve limb motor function and activities of daily living. The clinical effect is significant and worth learning from.