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目的探讨晚期肿瘤患者合并感染的病原菌分布及其相关因素。方法根据96例晚期肿瘤患者的病情及感染部位分别留取血、痰、分泌物、腹水和尿等标本进行培养,检测并鉴别致病菌。结果呼吸系统(71.9%)为最常见的感染部位,病原菌以革兰阴性菌(43.9%)为主,真菌占38.6%,革兰阳性菌占17.5%。结论晚期肿瘤患者感染概率较高,及时正确地留取标本、合理使用抗生素、加强营养支持、注意基础护理和消毒隔离等是预防和治疗感染的重要措施。
Objective To investigate the distribution of pathogens in patients with advanced cancer and their related factors. Methods Blood, sputum, secretions, ascites and urine samples were collected from 96 patients with advanced cancer and their infection sites. The pathogens were detected and identified. Results Respiratory system (71.9%) was the most common site of infection. Gram-negative bacteria (43.9%) were the main pathogens, with fungi accounting for 38.6% and gram-positive bacteria accounting for 17.5%. Conclusion Patients with advanced cancer have a higher probability of infection, timely and correctly taking samples, using antibiotics reasonably, strengthening nutritional support, and paying attention to basic nursing and disinfection and isolation are important measures to prevent and treat infections.