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目的观察低分子肝素联合阿司匹林在不稳定心绞痛治疗中的有效性和安全性。方法将28例不稳定心绞痛随机分为两组;对照组常规应用阿司匹林、硝酸酯类、倍他乐克、辛伐他汀。治疗组在对照组的基础上加用低分子肝素,5000u,2次/d,皮下注射。连用7d。住院中观察心绞痛发作的次数持续时间,心电图ST-T的变化及出血并发症。结果治疗组无论从心绞痛持续时间、发作次数,还是心电图ST-T的改善程度都明显优于对照组,且未发现严重出血并发症。结论低分子肝素联合阿司匹林可明显减轻症状。改善心肌缺血且未见明显出血反应。低分子肝素联合阿司匹林安全有效。
Objective To observe the efficacy and safety of low molecular weight heparin combined with aspirin in the treatment of unstable angina pectoris. Methods 28 cases of unstable angina pectoris were randomly divided into two groups; the control group routinely used aspirin, nitrates, Betaloc and Simvastatin. The treatment group in the control group based on the addition of low molecular weight heparin, 5000u, 2 times / d, subcutaneous injection. Used together 7d. The duration of angina pectoris episodes observed during hospitalization, ECG ST-T changes and bleeding complications. Results In the treatment group, no significant changes were found in the duration of angina pectoris, the number of seizures or ST-T electrocardiogram improvement, and no serious bleeding complications were found. Conclusion Low molecular weight heparin combined with aspirin can significantly reduce the symptoms. Improve myocardial ischemia and no significant bleeding reaction. Low molecular weight heparin combined with aspirin safe and effective.