晶状体上皮细胞终生不断地分裂和分化,形成晶状体纤维.这过程有一重要变化是细胞核的消失.对去核机理至今未明.Kuwabara等认为去核障碍可能导致白内障形成.为此,我们进行了细胞调节因子与晶状体细胞去核关系的探讨.我们用免疫细胞化学方法,对表皮生长因子(EGF)及其受体(EGF—R),C—jun和前列腺素合成酶等在晶状体上皮细胞均呈现阳性着色反应,而且相互关系密切.其中EGF—R的着色,在上皮细 Lens epithelial cells continue to divide and differentiate throughout the lifetime, the formation of lens fibers .An important change in this process is the disappearance of the nucleus .Nucleus mechanism for so far unknown.Kuwabara so that enucleation disorder may lead to cataract formation.To this end, we conducted a cellular regulation Factor and lens enucleation.We used immunocytochemistry to show positive expression of epidermal growth factor (EGF) and its receptor (EGF-R), C-jun and prostaglandin synthase in lens epithelial cells Coloring reaction, but also closely related to one of the EGF-R staining, the fine epithelium