扩张型心肌病(DC)是一种特发性心肌疾病,其特点是进行性心肌细胞破坏,最后导致纤维化,发病机制与自身免疫有关。以往研究表明,DC 病人血清中有心肌特异性抗体存在,但这些抗体的器官特异性和疾病特异性没有严格分析,这些抗体与骨骼肌有交叉反应,在其它心脏病中常有出现。本研究第一次 Dilated cardiomyopathy (DC) is an idiopathic cardiomyopathy characterized by progressive cardiomyocyte destruction that eventually leads to fibrosis, the pathogenesis of which is associated with autoimmunity. Previous studies have shown that there is a presence of cardiac-specific antibodies in the serum of DC patients, but the organ-specific and disease-specific antibodies are not rigorously analyzed. These antibodies cross-react with skeletal muscle and are often found in other heart diseases. This study first time