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目的探讨布拉氏酵母菌治疗婴幼儿轮状病毒性肠炎的临床疗效。方法 128例轮状病毒性肠炎患儿,按治疗方法不同分为观察组和对照组,各64例。对照组患儿给予常规对症治疗与合理喂养,观察组在对照组基础上加用布拉氏酵母菌散,对比两组临床疗效并记录患儿发热、呕吐、腹泻等主要临床症状消失时间、治愈时间及不良反应。结果观察组总有效率为93.75%,高于对照组的81.25%,差异有统计学意义(χ~2=4.57,P<0.05)。观察组患儿发热、呕吐、腹泻等主要临床症状消失时间和治愈时间均显著短于对照组,差异均具统计学意义(P<0.01)。治疗期间,两组均无明显不良反应发生。结论布拉氏酵母菌可缩短轮状病毒性肠炎患儿病程,促进恢复,临床疗效显著,且无明显不良反应,可作为治疗婴幼儿轮状病毒性肠炎的常规药物。
Objective To investigate the clinical efficacy of B. Cerevisiae in the treatment of infantile rotavirus enteritis. Methods A total of 128 children with rotavirus enteritis were divided into observation group and control group according to different treatment methods, each of 64 cases. Control group of children given conventional symptomatic treatment and rational feeding, the observation group in the control group based on the use of Brachyspira scattered, compared two groups of clinical efficacy and record children with fever, vomiting, diarrhea and other major clinical symptoms disappear time, cure Time and adverse reactions. Results The total effective rate in the observation group was 93.75%, which was higher than 81.25% in the control group (χ ~ 2 = 4.57, P <0.05). The disappearance time and the cure time of the main clinical symptoms such as fever, vomiting and diarrhea in the observation group were significantly shorter than those in the control group, with statistical significance (P <0.01). During treatment, no adverse reactions occurred in both groups. Conclusion Bladderworm can shorten the course of children with rotavirus enteritis and promote recovery. The clinical curative effect is remarkable, and there is no obvious adverse reaction, so it can be used as routine medicine for the treatment of rotavirus enteritis in infants and young children.