随着现代生活方式的改变,以中心性肥胖、胰岛素抵抗、高胰岛素血症、脂代谢紊乱、糖耐量异常、2型糖尿病、高血压等多重因素聚集为特征,以多个靶器官损害为主要改变的代谢综合征(SM)患者越来越多,而SM合并急性胰腺炎(AP)特别是重症急性胰腺炎(SAP)的发病率逐渐升高,有研究报道,SM与AP的严重程度及预后密切相关,临床可作为判断AP严重程度、预后的指标之一[1]。但是,目前SM合并AP的发病机制仍不十 With the changes of modern lifestyles, central obesity, insulin resistance, hyperinsulinemia, dyslipidemia, impaired glucose tolerance, type 2 diabetes mellitus, high blood pressure and other factors are characterized by aggregation, with multiple target organ damage as the main There are more and more patients with altered metabolic syndrome (SM), while the incidence of SM complicated with acute pancreatitis (AP), especially severe acute pancreatitis (SAP), is gradually increasing. Some studies have reported that the severity of SM and AP, Prognosis is closely related to the clinical can be used to determine the severity of AP, one of the indicators of prognosis [1]. However, the current pathogenesis of SM combined with AP is still not ten