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目的观察米索前列醇、尼尔雌醇、尼尔雌醇配伍米索前列醇用于绝经后妇女取器术前宫颈准备3种方法的效果。方法将对象按来站先后顺序随机分为A、B、C3组,A组:术前3小时予米索前列醇400μg放入阴道后穹窿。B组:尼尔雌醇4mg术前1周顿服;C组:术前1周尼尔雌醇4mg顿服,术前3小时阴道后穹窿放置米索前列醇400μg。结果宫颈软化C组最佳,C组与A、B两组比较差异有统计学意义(P<0.05),A、B两组比较差异无统计学意义(P>0.05)。取器效果C组比A、B两组好,C组分别与A、B两组比较差异有统计学意义(P<0.05)。A、B两组比较差异无统计学意义(P>0.05)。结论米索前列醇、尼尔雌醇用于绝经后妇女取器术前宫颈准备均有一定的效果,尼尔雌醇配伍米索前列醇用于绝经后妇女取器术前宫颈准备效果更好。
Objective To observe the effect of misoprostol, niletriol and nylestriol combined with misoprostol on preoperative cervical preparation in postmenopausal women. Methods The subjects were randomly divided into A, B and C3 groups according to the order of their stations. Group A: 400 μg of misoprostol was placed in the vaginal fornix three hours before operation. Group B: nilestriol 4mg preoperative 1 week Dayton clothing; Group C: 1 week before surgery nilestriol 4mg Dayton clothing, 3 hours before the vaginal fornix placed misoprostol 400μg. Results Cervical softening was the best in group C. The difference between group C and group A and B was statistically significant (P <0.05). There was no significant difference between group A and group B (P> 0.05). The effect of C group was better than that of A and B, and the difference between C group and A and B was statistically significant (P <0.05). There was no significant difference between A and B groups (P> 0.05). Conclusions Misoprostol and nilestiol are effective for pre-operative cervical preparation in post-menopausal women. Nilestriol and misoprostol are more effective for pre-operative cervical preparation in postmenopausal women .