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目的了解研究地区乙肝病毒感染孕产妇所生儿童接受预防乙肝母婴传播服务的效果,并比较不同干预措施的实施效果。方法由研究地区内医疗机构管理资料中筛选2008-2013年乙肝感染孕产妇,通过医院系统管理软件进行相关信息收集。回顾性调查云南省通海县通过孕产期保健服务发现的209例户籍乙肝病毒感染孕产妇所生儿童接受预防乙肝母婴传播干预措施(单一阻断措施和联合阻断措施)后,乙肝母婴传播阻断所取得的效果。应用SPSS17.0统计软件进行统计分析。结果 209例乙肝感染产妇所生儿童在出生后采用不同的乙肝阻断措施干预后,乙肝病毒母婴传播率为2.87%,采取单一阻断措施的发生率为10.87%,采取联合阻断措施的发生率为0.06%,两种阻断方式比较,差异具有统计学意义(χ~2=12.12,P<0.01)。结论采取两种干预措施均能有效预防乙肝母婴传播,而联合干预措施效果更好。
Objectives To understand the effects of preventing hepatitis B virus transmission from mother to child in children born to pregnant women with hepatitis B virus infection in a district and compare the effects of different interventions. Methods From 2008 to 2013, the pregnant women with hepatitis B infection were screened from the data of medical institutions in the study area, and the related information was collected through the hospital system management software. A retrospective survey of 209 pregnant women with HBV-infected mothers who were found in Tonghai County of Yunnan Province through maternal health services received interventions (single-block and combination-block) to prevent mother-to-child transmission of hepatitis B Disruption effect achieved. Application SPSS17.0 statistical software for statistical analysis. Results 209 maternal children with hepatitis B infection were intervened by different hepatitis B blockers after birth, the rate of mother-to-child transmission of hepatitis B virus was 2.87%, and the rate of single-block treatment was 10.87% The incidence was 0.06%. There were significant differences between the two methods (χ ~ 2 = 12.12, P <0.01). Conclusion Both interventions can effectively prevent mother-to-child transmission of hepatitis B, but the joint interventions are more effective.