本文就蟾毒灵对肝癌、肺癌、肠癌、胃癌、妇科肿瘤、胰腺癌、前列腺癌等多种肿瘤的抗肿瘤作用分子机制的研究进展进行系统综述,以期为蟾毒灵进一步的研究及扩大临床运用提供参考。认为蟾毒灵可以抑制多种实体肿瘤细胞增殖,诱导肿瘤细胞凋亡,促进肿瘤细胞分化,逆转肿瘤耐药,干扰细胞生长周期等。 This article systematically reviews the research progress of the molecular mechanism of bufalin on the anti-tumor effect of many tumors such as liver cancer, lung cancer, intestinal cancer, gastric cancer, gynecologic cancer, pancreatic cancer, prostate cancer and so on, in order to further study and expand the bufalin Clinical application of reference. That Bufalin can inhibit a variety of solid tumor cell proliferation, induce apoptosis of tumor cells and promote tumor cell differentiation, reversal of tumor resistance, interfering with cell cycle and so on.