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〖目的〗探讨简易鼻塞持续气道正压呼吸支持(NCPAP)装置在婴幼儿危重症中的应用。〖方法〗购买空氧混合仪,加温湿化罐等配件,设计组装简易NCPAP装置,于2001年1月至2002年5月,对本院53例患肺炎、毛细支气管炎、左向右分流先天性心脏病等合并有呼吸衰竭的患儿给予NCPAP,观察其对改善血pH、二氧化碳分压(PaCO2)、氧合(PaO2/FiO2)及呼吸频率(R)、心率(P)效果,预后和相关不良反应。〖结果〗应用NCPAP后53例中40例呼吸困难吸气三凹征和气促程度在1～6h内消失,11例有改善,2例病情加重。对资料完整的20例统计,NCPAP(1～6h)后氧合显示改善(P<0.05),pH与PaCO2的变化无显著差异性(P>0.05)。〖结论〗简易NCPAP装置用于婴幼儿呼吸衰竭安全而有效。
Objective To investigate the application of simple nasal continuous positive airway pressure support (NCPAP) device in infant critical illness. 〖Method〗 Buy air oxygen mixer, heating humidification tank and other accessories, design and assembly of simple NCPAP device, from January 2001 to May 2002, 53 patients with pneumonia in our hospital, bronchiolitis, left to right shunt Congenital heart disease and other patients with respiratory failure were given NCPAP to observe its effects on improving blood pH, PaCO2, PaO2 / FiO2 and respiratory rate, heart rate, And related adverse reactions. 〖RESULTS〗 Forty-three cases of dyspnea in 38 cases of NCPAP were disappeared within 1 ~ 6 hours, 11 cases were improved, and 2 cases were exacerbated. Data from the complete 20 cases of statistics, NCPAP (1 ~ 6h) after oxygen showed improved (P <0.05), pH and PaCO2 no significant difference (P> 0.05). Conclusion The simple NCPAP device is safe and effective for respiratory failure in infants and young children.