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目的 :研究人参皂苷对胃癌细胞、大肠癌细胞的作用。方法 :采用噻唑蓝 (MTT)比色法测定胃癌 38例、大肠癌 40例癌细胞对人参皂苷及 8种常用化疗药物的敏感性。结果 :人参皂苷对大肠癌敏感 ,对胃癌不敏感 ,其作用明显低于 5 氟脲嘧啶、丝裂霉素、平阳霉素、噻替派、足叶乙苷。结论 :人参皂苷可用于配合其它化疗药辅助治疗肠癌及胃癌。
Objective: To study the effects of ginsenosides on gastric cancer cells and colorectal cancer cells. Methods : MTT assay was used to detect the sensitivity of 38 cases of gastric cancer and 40 cases of colorectal cancer cells to ginsenosides and 8 commonly used chemotherapy drugs. RESULTS: Ginsenosides were sensitive to colorectal cancer and insensitive to gastric cancer. Their effects were significantly lower than 5 fluorouracil, mitomycin, pingyangmycin, thiotepa, and etoposide. Conclusion : Ginsenosides can be used in combination with other chemotherapeutics to treat colorectal cancer and gastric cancer.