论文部分内容阅读
We conducted a retrospective analysis of 221 subjects with 256 suspected gastrointestinal lesions from 2007 to 2015 to explore the detecting efficiency of dualtime-point fluorine-18 fludeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) and pathology examination.The abdominal delayed PET/ CT was performed within 45 min of the conventional scan.The change in maximum standardized uptake value (△SUVmax) and morphological features of the suspected lesions between the conventional and dual-time-point PET/ CT were compared.The sensitivity,specificity,positive predictive value,and negative predictive value (NPV) of conventional PET/CT were 81.6％ (84/103),56.2％ (86/ 153),55.6％ (84/151),and 81.9％ (86/105),respectively.Those of dual-time-point PET/CT were 94.1％ (97/103),78.4％ (120/153),74.6％ (97/130),and 95.2％ (120/126),respectively.There was a significant difference between the conventional and dual-time-point PET/CT (P ＜ 0.005).The SUVearly and the ％△SUVmax could not present more information in differential diagnoses,but the rate of tumors with increased SUVdelay accounted for 79.6％ (82/103) and more than that of nonneoplastic lesions (15.5％,29/187) (x2=115.5,P＜0.01).Therefore,the dual-time-point 18F-FDG PET/CT had a higher sensitivity and NPV than the conventional PET/CT to detect gastrointestinal tumors.The constant morphology and increased SUVde1ay help to detect the tumors and adding delayed imaging on the locality will be an effective method when we accidentally find a suspected gastrointestinal tumor on the conventional PET/CT images.