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目的分析地屈孕酮联合绒毛膜促性腺激素(HCG)对先兆流产患者临床症状及激素水平的影响。方法选取2014年4月至2016年9月接受治疗的90例先兆流产患者,将所有患者随机分为两组,每组45例。对照组采用黄体酮联合HCG治疗,观察组采用地屈孕酮联合HCG治疗。对比两组保胎成功率、临床症状、治疗前后激素水平及不良反应发生率。结果对照组保胎成功率低于观察组,观察组患者临床症状缓解时间及激素水平恢复时间、不良反应发生率均优于对照组,差异有统计学意义(P<0.05);治疗前后,两组患者孕激素水平及HCG水平比较差异均未见统计学意义(P>0.05)。结论地屈孕酮联合HCG在治疗先兆流产中对缓解患者的病情具有重要作用,同时可在短时间内恢复患者自身孕激素水平,且具有较高的安全性,在临床应用中具有较高的推广价值。
Objective To analyze the effect of dydrogesterone combined with chorionic gonadotropin (HCG) on clinical symptoms and hormone levels in patients with threatened abortion. Methods 90 cases of threatened abortion treated from April 2014 to September 2016 were selected and all patients were randomly divided into two groups of 45 cases. The control group was treated with progesterone plus HCG, and the observation group was treated with dydrogesterone combined with HCG. Contrast two groups of miscarriage success rate, clinical symptoms, hormone levels before and after treatment and the incidence of adverse reactions. Results The success rate of miscarriage in the control group was lower than that in the observation group. The relief time of the clinical symptoms, the recovery time of hormone levels and the incidence of adverse reactions in the observation group were better than those in the control group (P <0.05). Before and after treatment, There was no significant difference in progesterone level and HCG level between the two groups (P> 0.05). Conclusion Dydrogesterone combined with HCG plays an important role in alleviating the patient’s condition in the treatment of threatened abortion. At the same time, it can restore the patient’s own progesterone level in a short period of time and has higher safety. In the clinical application, Promote value.