论文部分内容阅读
目的 :通过尿液白蛋白 (Alb)和α1 微球蛋白 (α1 MG)含量测定 ,以早期诊断糖尿病肾损害。方法 :采用免疫速率散射比浊法 ,对 3 9例健康者 ,73例糖尿病 (DM)患者Alb ,α1 MG联合检测。结果 :尿Alb和α1 MG排泄水平均有明显增加 (P <0 0 1)。尿α1 MG升高者占 75 3 % ,Alb升高者占 4 5 2 %。结论 :尿α1 MG测定在早期发现糖尿病肾病有更大的敏感性。
OBJECTIVE: To diagnose early diabetic nephropathy by measuring the levels of urinary albumin (Alb) and α1 microglobulin (α1 MG). Methods: The immune rate nephelometry was used to detect Alb and α1 MG in 39 healthy controls and 73 diabetic patients. Results: Urinary Alb and α1 MG excretion levels were significantly increased (P <0.01). Urine α1 MG elevated 75 3%, Alb elevated 45 2%. Conclusions: Urinary α1 MG assay has greater sensitivity to early detection of diabetic nephropathy.