转铁蛋白受体(Transferrin Receptor; TR)大量存在幼雅红细胞和网织红细胞中,担负摄取铁离子的主要任务.作者曾发现TR在体外从细胞表面大量释放,利用已知的两种抗单克隆抗体OKTg,B3/25进行双夹心放射免疫测定(Sand wich RIA)证明了正常人血清中含有免疫活性的TR,并认为其机理就是由上述释放造成的.另外,血清中出现游离TR,可能反映人体组织富含TR的红细胞系质量(Eerythroid mass).因此,作者除用本法检测 Transferrin Receptor (TR) is present in large numbers in young erythrocytes and reticulocytes and is responsible for the uptake of iron ions. The authors have found that TR is released in large quantities from the cell surface in vitro using two known anti-single Sandwich RIA, a clone of OKTg and B3 / 25, demonstrated the immunogenicity of TR in normal human serum and is believed to be due to the above-mentioned release. In addition, the presence of free TR in serum may Reflect the body mass of TR-rich erythrocytes quality (Eerythroid mass). Therefore, the author except using this method test