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目的 探讨原发性腹膜后及肠系膜脂肪肉瘤的外科治疗方法。方法 回顾性分析 1993~ 2 0 0 1年收治的 18例原发性腹膜后及肠系膜脂肪肉瘤病人经手术治疗 2 7例次的临床资料。结果 脂肪肉瘤占同期经手术探查的原发性腹膜后及肠系膜实体瘤的 31 6 % (18/ 5 7) ;临床表现主要为进行性增大的腹部包块与消化道症状 ;病理类型以高分化型多见 (13/ 18) ;首诊后 16例获得临床根治性切除 ,6例复发性脂肪肉瘤病人 ,共接受 15次手术 ;全组合并单侧肾切除 6例 ,部分结肠切除 4例 ,部分空肠切除和胃大部切除各 1例 ;肠系膜脂肪肉瘤手术多采用完整切除术 (8/ 10 )。结论 手术切除是目前唯一有效的治疗方法 ,必要时可行联合脏器切除术 ,但不应强求根治 ;为改善生存质量、延长生存期 ,对多发肿瘤不能完整切除者应积极实施姑息性减瘤术 ,多次复发者有条件可多次手术 ;采用完整切除术、尽量避免肠切除治疗对多发性及复发性肠系膜脂肪肉瘤具有重要临床价值。
Objective To investigate the surgical treatment of primary retroperitoneal and mesentery liposarcoma. Methods The clinical data of 18 cases of primary retroperitoneal and mesentery liposarcoma treated by surgery in 27 cases between 1993 and 2001 were retrospectively analyzed. Results Liposarcoma accounted for 31 6% (18/57) of primary retroperitoneal and mesentery solid tumors during the same period of operation. The clinical manifestations were mainly progressive abdominal masses and gastrointestinal symptoms. The pathological types were high Differentiated more common (13/18); the first diagnosis of 16 cases of clinical radical resection, 6 cases of recurrent liposarcoma patients, a total of 15 operations; unilateral combined nephrectomy in 6 cases, partial resection in 4 cases , Partial jejunal resection and subtotal gastrectomy in 1 case; mesentery liposarcoma surgery and more use of complete resection (8/10). Conclusions Surgical resection is the only effective treatment at present. If necessary, it is feasible to combine organ resection, but not radical cure. In order to improve the quality of life and prolong the survival period, we should actively implement palliative ablation , Multiple recurrence of conditional surgery can be multiple; the use of complete resection, try to avoid bowel resection treatment of multiple and recurrent mesenchial liposarcoma has important clinical value.