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目的了解克罗恩病(Crohn’sDisease.CD)在成都市的发病情况及临床病理特点。方法对成都市三家医院确诊的55例CD进行回顾性分析。结果(1)住院病例数逐年增加,但其住院构成比仍低。(2)回结肠受累最多(61.8%);腹痛(92.7%)为最主要临床表现;肠梗阻(45.5%)为最常见并发症。(3)肉芽肿检出率在手术标本为60%,活检标本为28.6%;(4)术前CD正确诊断率为29.1%,70.9%的病例被误诊,其中误诊为肠结核的最多(47.3%)。结论(1)成都市CD住院病例数逐年递增,反映了该市CD发病率增加的一个侧面。(2)CD临床表现复杂多样,误诊率极高,应特别注意与肠结核鉴别。(3)CD没有绝对形态学指标,肉芽肿检出率不高,诊断不应过分强调肉芽肿的存在。
Objective To investigate the incidence and clinicopathological features of Crohn’s disease (CD) in Chengdu. Methods Retrospective analysis of 55 cases diagnosed CD in three hospitals in Chengdu. Results (1) The number of hospitalizations increased year by year, but the hospitalization ratio was still low. (2) The most frequent ileocecal involvement (61.8%); abdominal pain (92.7%) was the most common clinical manifestations; intestinal obstruction (45.5%) was the most common complication. (3) The detection rate of granuloma was 60% in surgical specimens and 28.6% in biopsy specimens; (4) The correct diagnosis rate of preoperative CD was 29.1%, 70.9% of cases were misdiagnosed, of which misdiagnosed as intestinal tuberculosis Up to (47.3%). Conclusions (1) The number of CD inpatients in Chengdu increased year by year, reflecting one aspect of the increased incidence of CD in the city. (2) CD clinical complex and diverse, high misdiagnosis rate, special attention should be paid to identify with intestinal tuberculosis. (3) There is no absolute morphological index of CD, granuloma detection rate is not high, the diagnosis should not be too much emphasis on the presence of granuloma.