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目的探讨ABO新生儿溶血病与O型血孕妇IgG抗体效价的相关性。方法新生儿黄疸或高胆红素血症的患儿60例,患儿检查ABO血型、Rh血型及ABOHDN血型血清学3项(直接抗球蛋白试验、血清游离抗体试验及抗体释放试验),母亲查ABO、Rh血型和IgG抗A(B)抗体效价。结果60例黄疸患儿与其母均ABO血型不合,母亲的ABO血型均为“O”型。结论ABOHDN的发病随母体的IgG抗A(B)效价升高而升高。
Objective To investigate the relationship between ABO neonatal hemolytic disease and IgG antibody titer in O-pregnant women. Methods Sixty children with neonatal jaundice or hyperbilirubinemia were enrolled in this study. Three children with ABO blood group, Rh blood group and ABOHDN blood group (direct antiglobulin test, serum free antibody test and antibody release test), mothers Check ABO, Rh blood group and IgG anti-A (B) antibody titers. Results 60 cases of jaundice children with their mother average ABO blood group incompatibility, mother’s ABO blood group are “O” type. Conclusion The incidence of ABOHDN increased with the increase of maternal IgG anti-A (B) titer.