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已有研究证明,应用阿司匹林抗血小板治疗可减少冠状动脉疾病(coronary artery disease,CAD)患者的不良预后。阿司匹林不可逆地抑制血小板环加氧酶1(cyclooxygenase-1,COX-1)并减弱血栓烷A2(thromboxane A2,TXA2)介导的血小板聚集,但COX-1的抑制在不同病理情况下可变化。研究人员
Studies have shown that antiplatelet therapy with aspirin can reduce the adverse prognosis of patients with coronary artery disease (CAD). Aspirin irreversibly inhibits cyclooxygenase-1 (COX-1) and attenuates thromboxane A2 (TXA2) -mediated platelet aggregation, but the inhibition of COX-1 may vary under different pathological conditions. Researchers