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环糊精(CD)对于客体分子的包结作为一种酶-底物相互作用的模型而受到广泛的研究,但研究的对象大多为烃、脂肪醇、脂肪二醇、苯酚、环己烷衍生物、萘衍生物以及其他芳香化合物,而对于氨基酸分子的识别研究较少.我们曾报道环糊精双核铜配合物对于几种芳香氨基酸生物分子的识别能力,从主体环糊精与双核铜形成配合物的构型变化、多点识别和诱导楔合作用讨论了对于形成超分子体系的贡献.近来我们报道了单-[6-(1-吡啶)-6-脱氧]-α和γ-环糊精对非芳香氨基酸分子识别的热力学性质,给出了有意义的结果.然而由于环糊
Cyclodextrin (CD) has been extensively studied as an enzyme-substrate interaction model for inclusion of guest molecules, but most of the subjects studied are hydrocarbons, fatty alcohols, aliphatic diols, phenol, cyclohexane derived , Naphthalene derivatives and other aromatic compounds, and less recognition of amino acid molecules.We have reported cyclodextrin binuclear copper complexes for several aromatic amino acid biomolecules recognition ability, the formation of the main cyclodextrin and binuclear copper Contributions to the formation of supramolecular systems have been discussed with regard to their conformational changes, multi-site recognition, and induced wedge interactions.We recently reported that mono- [6- (1-pyridyl) -6-deoxy] -α and γ-rings The thermodynamic properties of non-aromatic amino acid recognition by dextrin give meaningful results However, due to the cyclodextrin