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本文检测了39例新生儿缺氧缺血性脑病(HIE)血清中超氧化物歧化酶(5OD)、过氧化氢酶(CAT)及脂质过氧化物(LPO)含量与30例正常新生儿比较,结果显示HIE患儿血中LPO较正常增高,而且,急性期高于恢复期、重度高于中度,SOD及CAT均较正常减低,而且急性期低于恢复期,重度低于中度,统计学处理差异均显著。并观察了自由基清除剂对HIE的疗效。
In this study, 39 cases of neonatal hypoxic-ischemic encephalopathy (HIE) serum superoxide dismutase (5OD), catalase (CAT) and lipid peroxides (LPO) content compared with 30 normal newborns , The results showed that LPO in children with HIE was higher than normal, and the acute phase was higher than the recovery, severe higher than moderate, SOD and CAT were lower than normal, and the acute phase was lower than the recovery, severe lower than moderate, Statistical differences were significant. And observed the effect of free radical scavenger on HIE.