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目的对河南省开封市2010年流行性感冒(流感)监测结果进行分析,了解流感的流行趋势、病原学变化特点,为今后流感防治工作提供科学指导。方法哨点医院对流感样病例(ILI)进行监测,并按要求采集ILI咽拭子标本运送至流感监测网络实验室,流感监测网络实验室在24小时内采用real-time RT-PCR法进行核酸检测,并完成流感病毒的分离鉴定。结果 2010年开封市流感监测哨点医院共监测门、急诊就诊病例91 661例,ILI 853例。病例以25岁～年龄组为主(占35.99%),60岁～年龄组最少。第1周(1月4-10日)至第18周(5月3-9日),25岁～和15岁～年龄组所占比例较大,但自第43周(10月25-31日)开始,以0岁～年龄组为主。全年共采集ILI咽拭子标本571例,经实验室检测,新甲H1N1流感病毒18例(占3%),A未分型57例(占10%),B型9例(占2%),季H1和季H3均未检出,全年无流感及甲型H1N1流感暴发疫情的发生。结论流感发病有季节性,2010年第3周ILI数达高峰,随后呈明显下降趋势,ILI构成以25岁～年龄组为主,流感病毒以A未分型为优势流行株。
Objective To analyze the surveillance results of influenza in 2010 in Kaifeng City, Henan Province, and to understand the epidemiological trend of influenza and the characteristics of pathogenic changes, so as to provide scientific guidance for the prevention and control of influenza in the future. Methods Sentinel Hospital monitored influenza-like illness (ILI) and collected ILI throat swab specimens as required to be sent to the Influenza Surveillance Network Laboratory. Real-time RT-PCR was performed within 24 hours by the Influenza Surveillance Network Laboratory Detection, and complete the identification of influenza virus isolation. Results In 2010, 91 661 cases of emergency visits and 853 cases of ILI were monitored in the flu surveillance sentinel hospitals in Kaifeng City. Cases of 25-year-old age group (35.99%), 60-year-old group with the least. The first week (January 4-10) to the 18th week (May 3-9), 25-year-old and 15-year-old age group accounted for a large proportion, but since the 43th week (October 25-31 Day) to 0 years old ~ age group based. A total of 571 ILI throat swabs were collected during the year. After laboratory tests, 18 cases (3%) of the new H1N1 influenza virus, 57 cases (10%) of A undifferentiated, 9 cases of type B (2% ), Season H1 and season H3 were not detected, year-round influenza-free and outbreaks of influenza A (H1N1) outbreaks. Conclusion The incidence of influenza is seasonal. The number of ILI peaked in the third week of 2010, then decreased significantly. ILI was mainly composed of 25 years old and the age group. Influenza virus was classified as the predominant epidemic strain.