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自从 194 1年Haggin和Hodges发现前列腺癌的雄激素依赖性以来 ,抗雄激素治疗一直为前列腺癌的主要治疗手段。随着 1971年发现PSA (前列腺特异抗原 )并于 1979年成功用于临床 ,PSA对前列腺癌的诊断、分期、预后以及监测治疗的敏感性具有重大意义[1] 。中晚期
Anti-androgen therapy has been the primary treatment for prostate cancer since Haggin and Hodges discovered the androgen dependence of prostate cancer in 1941. With the discovery of PSA (Prostate Specific Antigen) in 1971 and successful clinical use in 1979, PSA is of great importance for the diagnosis, staging, prognosis and sensitivity of treatment for prostate cancer [1]. In the late