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目的:探讨小梁切除术中使用MMC 联合术后激光断线术的疗效及方法。方法:将68 例(93只眼) 青光眼随机分为A 组和B 组。A 组35 例(48 只眼) ,小梁切除术中使用 MMC,紧密缝合巩膜瓣,术后激光断线;B 组33 例(45 只眼) ,术中使用MMC,常规缝合巩膜瓣,术后不断线。观察术后眼压、视力、滤过泡、前房、眼底等。结果:A 组平均随诊11-89 ±1-93 个月,手术成功率95-8 % ;B 组平均随诊12-24±1-61 个月,手术成功率91-1 % ,二者对比无显著意义,术后眼压4 周内二组对比有显著性,4 周以后至最近一次随诊观察无显著性。低眼压、浅前房、脉络膜脱离、黄斑水肿,视力下降等并发症A 组较B 组显著减少。结论:A 组方法既可避免术后早期滤过过强引起的并发症又能抑制瘢痕化,改善滤过。
Objective: To investigate the efficacy and methods of laser disconnection using MMC combined with trabeculectomy in trabeculectomy. Methods: 68 cases (93 eyes) of glaucoma were randomly divided into A group and B group. A group of 35 patients (48 eyes), trabeculectomy using MMC, close the scleral flap, postoperative laser disconnection; B group of 33 patients (45 eyes), the use of MMC, routine suture scleral flap surgery After continuous line. Postoperative intraocular pressure, visual acuity, filtration bleb, anterior chamber, fundus and so on. Results: The average follow-up time in group A was 11-89 ± 1-93 months, the success rate was 95-8%. The average follow-up time in group B was 12-24 ± 1-61 months, the operation success rate was 91-1% There was no significant difference between the two groups after 4 weeks of intraocular pressure, and no significant difference was observed after 4 weeks to the last follow-up. Low intraocular pressure, shallow anterior chamber, choroidal detachment, macular edema, visual acuity and other complications A group was significantly reduced compared with the B group. Conclusion: The method of group A can not only prevent the early postoperative complications caused by excessive filtration but also inhibit scarring and improve filtration.