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目的研究醒脑静治疗重度颅脑损伤时患者急性期脑血管痉挛的发生率,从而降低迟发性神经功能缺损的发生率。方法选择重度颅脑损伤患者分为对照组和治疗组,治疗组在西医治疗的基础上配合应用醒脑静针剂治疗,经颅多普勒超声检查两组患者入院第2、4、7、14、21天脑血管痉挛的发生率,统计分析中西医结合治疗的优势。结果入院第2、4、7、14、21天两组患者脑血流速度及脑血管痉挛发生率差异存在统计学意义(P<0.05),其中第4天差异最为显著。结论在西医治疗的基础上加用醒脑静可以降低重度颅脑损伤后颅内血流速度,防治脑血管痉挛。
Objective To study the effect of Xingnaojing on the incidence of acute cerebral vasospasm in patients with severe craniocerebral injury, so as to reduce the incidence of delayed neurological deficits. Methods The patients with severe craniocerebral injury were divided into control group and treatment group. The treatment group was treated with Xingnaojing injection on the basis of Western medical treatment. Transcranial Doppler ultrasound examination was performed on the 2, 4, 7, 14 , 21-day incidence of cerebral vasospasm, statistical analysis of Integrative Medicine advantage. Results There were significant differences in cerebral blood flow velocity and incidence of cerebral vasospasm between the two groups on the 2nd, 4th, 7th, 14th and 21st days on admission (P <0.05), with the most significant difference on the 4th day. Conclusion Western medicine treatment based on the use of Xingnaojing can reduce intracranial blood flow after severe head injury, prevention and treatment of cerebral vasospasm.