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CNTF具有广泛的神经营养活性 ,可能在神经发育与再生修复中发挥重要作用。有关 CNTF在大鼠脊髓组织中的表达尚不清楚 ,我们在制备抗人 CNTF多克隆抗体的基础上 ,利用免疫组化及原位杂交的方法系统的研究了成年大鼠脊髓组织 CNTF与受体 CNTFRα的分布与细胞定位。免疫组化结果显
CNTF has a wide range of neurotrophic activity and may play an important role in neurodevelopment and regenerative repair. The expression of CNTF in rat spinal cord tissue is unclear. Based on the preparation of anti-human CNTF polyclonal antibody, we used immunohistochemistry and in situ hybridization to systematically study the effects of CNTF and receptor CNTFRα Distribution and Cell Localization. Immunohistochemical results were significant