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目的:观察复方苦参注射液对恶性肿瘤化疗中的毒副作用的影响。方法:330例恶性肿瘤患者随机分为对照组150例采用常规治疗,实验组180例在常规治疗基础上联用复方苦参注射液治疗。结果:①实验组近期疗效与对照组差异无统计学意义(P>0.05);②毒副反应实验组较对照组有统计学意义(P<0.05);③化疗后生存质量改善方面,实验组优于对照组(P<0.05)。实验组病灶完全缓解及部分缓解共计121例,总有效率67.22%,对照组为97例,总有效率64.67%,两组无显著性差异(P>0.05)。结论:在常规治疗基础上联用复方苦参注射液能明显减轻恶性肿瘤化疗中的毒副作用,提高患者对化疗的耐受能力,改善患者的一般状况,提高患者生存质量。
Objective: To observe the effect of Compound Kushen Injection on the side effects of chemotherapy in malignant tumor. Methods: A total of 330 patients with malignant tumor were randomly divided into control group (n = 150) and conventional treatment. The experimental group (n = 180) was treated with Compound Kushen Injection on the basis of routine treatment. Results: ① There was no significant difference in the short-term curative effect between the experimental group and the control group (P> 0.05); ② The toxicity of the experimental group was significantly higher than that of the control group (P <0.05); ③The quality of life of the experimental group Better than the control group (P <0.05). The complete remission and partial remission of the experimental group were 121 cases in total, the total effective rate was 67.22%. The control group was 97 cases, the total effective rate was 64.67%. There was no significant difference between the two groups (P> 0.05). Conclusion: The combination of compound Kushen injection on the basis of conventional treatment can significantly reduce the side effects of chemotherapy in malignant tumors, improve patient tolerance to chemotherapy, improve the general condition of patients and improve the quality of life of patients.