纳洛酮联合醒脑静注射液治疗急性重度乙醇中毒的疗效观察

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目的:分析纳洛酮联合醒脑静注射液治疗急性重度乙醇中毒的效果。方法:随机抽取2014年9月至2016年3月六盘水市钟山区人民医院收录的80例急性乙醇中毒患者,患者呈昏迷状态;采用分组法讨论,每组40例,对照组为纳洛酮注射液,观察组为纳洛酮联合醒脑静注射液,所有患者于注射后7 d回访调查,结合治疗前后症状消失情况进行对比分析。结果:对照组20例非常满意,13例满意,5例不满意,2例非常不满意;观察组35例非常满意,4例满意,仅1例不满意;两组患者注射后治疗满意度对比,差异具有统计学意义(P<0.05)。结论:联合治疗采用纳洛酮联合醒脑静注射液,总体效果更好,注射后苏醒时间、思维意识、肢体功能等均优于对照组,需倡导联合治疗。 Objective: To analyze the effect of naloxone combined with xingnaojing injection in treating acute severe alcoholism. Methods: Eighty patients with acute ethanol poisoning were enrolled randomly from September 2014 to March 2016 in Zhong Shan District People’s Hospital of Liupanshui City. The patients were in a coma. The grouping method was used to discuss 40 patients in each group. The control group was naloxone injection The observation group was naloxone combined with xingnaojing injection. All the patients were investigated retrospectively on the 7th day after injection and compared with the disappearance of the symptoms before and after treatment. Results: In the control group, 20 cases were very satisfied, 13 cases were satisfied, 5 cases were unsatisfied and 2 cases were dissatisfied. 35 cases in the observation group were very satisfied, 4 cases were satisfied and 1 case was not satisfied. , The difference was statistically significant (P <0.05). Conclusion: Combination therapy with naloxone combined with xingnaojing injection has better overall effect. After injection, recovery time, thinking and physical function are superior to the control group, and combined therapy should be advocated.
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